Voluntary and sign a consent form; pikkelyes papilloma histo.
Age years old, gender unlimited; 3. Histology or imaging diagnosed as diffuse intrinsic pontine glioma, patients haven't received any anti-tumor treatment; 4.
According to the RANO criteria, at least one measurable lesion; 5. Fertile subjects are willing to take contraceptive measures during the study period.
Exclusion Criteria: 1. Recurrent DIPG; 2.
Have received any other anti-tumor treatment for DIPG, including surgical treatment except biopsychemotherapy, radiotherapy, targeted drugs, immunotherapy, etc; 3.
Human immunodeficiency virus HIV infection or active hepatitis B infection or hepatitis C infection; 5. Major operation except biopsy were performed within four weeks before inclusion; 7.
Decompensated heart failure NYHA grades III and IVunstable angina, acute myocardial infarction, persistent and clinically significant arrhythmia within three months of inclusion; 8. Have other malignant tumor history; 9.
Known allergy to Nimotuzumab, temozolomide or its analogues or any component of the prescription; Unable to tolerate radiotherapy; Other reasons that are not suitable to participate in this study according to the researcher's judgment. Nem: All.